Lock in Moisture Without Clogging Your Pores With Squalane-Infused Skincare
Plant-derived squalane is suitable hydration-booster that tends to work well with all skin types.

Scouted/The Daily Beast/Retailers.
Scouted selects products independently. If you purchase something from our posts, we may earn a small commission.
A strong skin barrier is the key to a healthy complexion since it protects against harmful external factors such as pollution and toxins. With that in mind, it‘s key to incorporate barrier-strengthening ingredients—such as squalane, known for its reparative and moisturizing properties—into your daily (or nightly) skincare regimen. Not only does this powerful emollient block the irritants and environmental aggressors from penetrating the skin barrier, but it also helps prevent water loss for hydrated skin.
“Squalene helps hydrate and smooth skin without clogging pores. It’s a good emollient, helping to hydrate and soften the skin by forming a barrier to prevent moisture loss,” says Dr. Purvisha Patel, MD.
Plus, it‘s also a great antidote to keep on hand if you’re experiencing irritation, dryness or redness from ingredients like vitamin A (retinoids) and chemical or physical exfoliants. Unlike retinoids and exfoliants, however, squalane is also well-tolerated by most skin types because it mimics your skin’s natural oils. “It has some antioxidant properties. It can also soothe inflammation and is noncomedogenic, making it good for acne-prone skin,” Dr. Patel says.
It’s important to note the difference between squalane and squalene. The former, with an “a,” is a derivative of the latter with an “e,” which is naturally produced by the body. (It’s also found in, get this, shark liver.) However, the former is more commonly found in skin-care products due to its longer shelf life. Nowadays, most squalane found in skin-care products is plant-derived due to ethical concerns.
Get the best of The Beast delivered right to your inbox
By clicking “SUBSCRIBE” you agree to our Terms of Use and Privacy Policy.
Ahead, we’ve rounded up the best squalane-enriched skin-care products, including moisturizers, balms, serums, and cleansers to support a healthy, strong skin barrier.

Fresh Rose & Squalane Deep Hydration Oil-Infused Serum

Biossance Squalane + Zinc Sheer Mineral Sunscreen

First Aid Beauty Retinol Eye Cream with Squalane + Ceramides

Kiehl's Ultra Facial Skin Barrier Repair Balm

The Outset Nourishing Squalane Daily Moisturizer
Unlock a year of full access to The Looker and The Daily Beast for $35.
Monthly
$1
First month then $5.99/month
Annual
$35
First year then $59.99/year
Premium
$79
First year then $119.99/year
*Substack access provided by the next business day, using your subscription email. Choosing the Premium plan constitutes your permission to share your subscription email with Substack and your agreement to Substack’s Privacy Policy.
Looks like you already have a subscription!
You're all set!
Thanks for subscribing.
Register below to read this article for free or subscribe
to unlock unlimited access to The Looker and The Daily Beast.
Monthly
$1
First month then $5.99/month
Annual
$35
First year then $59.99/year
Premium
$79
First year then $119.99/year
*Substack access provided by the next business day, using your subscription email. Choosing the Premium plan constitutes your permission to share your subscription email with Substack and your agreement to Substack’s Privacy Policy.
Already have an account? Sign In
Looks like you already have a subscription!
You're all set!
Thanks for subscribing.
Sign in
Login dialog
